Smoking reduces insulin absorption from subcutaneous tissue.

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Smoking reduces insulin absorption from subcutaneous tissue.

The degree of glycaemic control in insulin-dependent diabetic patients is highly influenced by the rate of insulin absorption from subcutaneous tissue to blood. We have recently shown a correlation between subcutaneous blood flow and insulin absorption.' Smoking increases the concentration of catecholamines in the blood.2 In normal subjects inhaling cigarettes produces a transient rise in blood...

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The effect of the Finnish sauna on insulin absorption from a subcutaneous injection site was examined in eight insulin-dependent diabetic patients by measuring externally the disappearance rate of 125I-labelled rapid-acting insulin. The sauna (twice for 25 minutes at 85 degrees C) accelerated insulin absorption by 110% as compared with room temperature (p < 0.01). After the sauna blood glucose ...

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BACKGROUND Worldwide, ∼1 million people manage their type 1 diabetes with an insulin pump and a continuous subcutaneous insulin infusion (CSII) catheter. Patients routinely insert a new catheter every 2-3 days due to increasing variability of insulin absorption over time. Catheter insertion and maintenance damage capillaries, lymphatics, cells, and connective tissue leading to an acute inflamma...

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The question is, is insulin absorption after subcutaneous (SC) injection of a prandial insulin/insulin analog prior to a meal comparable to that of infusion of the same insulin dose as a bolus via an insulin pump? You might say, this is easy; let us check what published studies tell us about this topic. A search in PubMed using search terms, “injection infusion insulin subcutaneous pharmacokine...

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ژورنال

عنوان ژورنال: BMJ

سال: 1982

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.284.6311.237